Prepare the Savory Spread: In a small mixing bowl, thoroughly combine the light mayonnaise, ketchup, dill pickle relish, and smoked paprika. Season with a small pinch of fine sea salt and ground black pepper to taste. Stir well, then cover and place in the refrigerator to chill while you prepare the rest of the meal.

Form the Beef Patties: In a medium mixing bowl, add the lean ground beef. Drizzle the Worcestershire sauce over the beef, then sprinkle with the seasoned salt and 1/2 teaspoon of black pepper. Gently combine the ingredients with your hands, being careful not to overmix (which can make the patties tough). Divide the beef mixture into three equal portions. Shape each portion into a firm patty, approximately 3/4-inch thick.

Cook the Patties: Heat a large, heavy-bottomed skillet or a grill pan over medium to medium-high heat. Once hot, carefully place the formed patties onto the cooking surface. Allow space between them; for three patties, this should not be an issue in a standard large skillet. Cook the patties for approximately 3-5 minutes on the first side. Flip carefully and cook for another 3-5 minutes on the second side, or until they reach your preferred level of doneness. For safety, ground beef should be cooked to an internal temperature of at least 160∘F (71∘C).

Melt Cheese: During the final minute of cooking, place one slice of American cheese on top of each patty. Allow the cheese to melt slightly before removing the patties from the heat.

Assemble the Lettuce Cups: Lay out three large lettuce leaves on individual plates or a serving platter. Place one cheese-topped beef patty into each lettuce leaf. Spoon a generous amount of the chilled savory spread over each patty. Finish by topping with a few thin slices of tomato and red onion, according to preference.

Serve: To eat, gently fold the sides of the lettuce leaf around the fillings to create a handheld cup. Serve immediately and enjoy!